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A Dual Tactic: Antibodies Broadly Neutralize Influenza B Relying on "Receptor Mimicry" and "Locking onto Sugar Shield"
Influenza A and B viruses are the primary drivers of annual acute respiratory infections, commonly known as the flu, and represent a persistent public health challenge.
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BMAL2 is a druggable target for ovarian clear cell carcinoma (OCCC)
Ovarian clear cell carcinomas (OCCC), particularly cases retaining wild-type ARID1A expression, are chemo-resistant and lack specific therapies. We identified circadian gene BMAL2 as a critical oncogene that promotes OCCC tumorigenesis by preventing endogenous DNA damage.
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