化學生物學研究領域 2016

Chen, Yun-Ru Ruby

  • Smethurst, Phillip*; Newcombe, Jia; Troakes, Claire;Simone, Roberto; Wadsworth, John; Hardy, John; Chen, Yun-Ru; Patani, Rickie; Sidle, Katie, 2016, “ In vitro prion-like mechanisms of TDP-43 in ALS”, NEUROBIOLOGY OF DISEASE, 96, 236-247. (SCIE) (IF: 5.332; SCIE ranking: 17.6%)
  • Nguyen Quoc Thai, Ning-Hsuan Tseng, Mui Thi Vu, Tin Trung Nguyen, Huynh Quang Linh, Chin-Kun Hu*, Yun-Ru Chen*, and Mai Suan Li*, 2016, “Discovery of DNA dyes Hoechst 34580 and 33342 as good candidates for Alzheimer’s disease: in silico and in vitro study”, JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 30(8), 639-50. (SCIE) (IF: 2.546; SCIE ranking: 64.3%,46.5%,48.6%)
  • Yu-Jen Chang, Nguyen Hoang Linh, Hui-Ming Yu, Mai Suan Li*, and Yun-Ru Chen*, 2016, “Alzheimer’s Amyloid-β Sequesters Caspase-3 in vitro via its C-terminal Tail.”, ACS Chemical Neuroscience, 7(8), 1097-1106. (SCIE) (IF: 4.486; SCIE ranking: 19.7%,25.9%,24.3%)
  • Yu-Jen Chang, U-Ser Jeng, Ya-Ling Chiang, Ing-Shouh Hwang, and Yun-Ru Chen*, 2016, “Glycine-Alanine Dipeptide Repeat from C9orf72 Hexanucleotide Expansions Forms Toxic Amyloids Possessing Cell-to-cell Transmission Property”, Journal of Biological Chemistry, 291(10), 4903-4911. (SCIE) (IF: 4.238; SCIE ranking: 29.3%)
  • Chia‑Wei Lee, Lan‑Ling Jang, Huei‑Jyuan Pan, Yun‑Ru Chen, Chih‑Cheng Chen, and Chau‑Hwang Lee*, 2016, “Membrane roughness as a sensitive parameter reflecting the status of neuronal cells in response to chemical and nanoparticle treatments”, Journal of Nanobiotechnology, 14, 9. (SCIE) (IF: 6.518; SCIE ranking: 46.2%,84.8%)

Cheng, Wei-Chieh

  • Lin CK, Yun WY, Lin LT, Cheng WC, 2016, “A concise approach to the synthesis of the unique N-mannosyl d-beta-hydroxyenduracididine moiety in the mannopeptimycin series of natural products.”, Organic & biomolecular chemistry, 14(17), 4054-4060. (SCIE) (IF: 3.412; SCIE ranking: 22.8%)
  • Cheng WC, Wang JH, Li HY, Lu SJ, Hu JM, Yun WY, Chiu CH, Yang WB, Chien YH, Hwu WL, 2016, “Bioevaluation of sixteen ADMDP stereoisomers toward alpha-galactosidase A: Development of a new pharmacological chaperone for the treatment of Fabry disease and potential enhancement of enzyme replacement therapy efficiency.”, European journal of medicinal chemistry, 123, 14-20. (SCIE) (IF: 5.573; SCIE ranking: 8.2%)
  • Lin CK, Hou CC, Guo YY, Cheng WC, 2016, “Design and Synthesis of Orthogonally Protected d- and l-beta-Hydroxyenduracididines from d-lyxono-1,4-Lactone.”, Organic letters, 18(20), 5216-5219. (SCIE) (IF: 6.091; SCIE ranking: 7%)
  • Chen KT, Chen PT, Lin CK, Huang LY, Hu CM, Chang YF, Hsu HT, Cheng TJ, Wu YT, Cheng WC, 2016, “Structural Investigation of Park's Nucleotide on Bacterial Translocase MraY: Discovery of Unexpected MraY Inhibitors.”, Scientific reports, 6, 31579. (SCIE) (IF: 3.998; SCIE ranking: 23.9%)

Li, Tsung-Lin

  • L. J. Hsu, N. S. Hsu, Y. L. Wang, C. J. Wu, T. L. Li*, 2016, “Structural and biochemical interrogation on transketolase from Pichia stipitis for new functionality”, PROTEIN ENGINEERING DESIGN & SELECTION, 29(11), 513-522. (SCIE) (IF: 1.774; SCIE ranking: 76.9%,83.2%)
  • H. J. Chai, C. J. Wu, S. H. Yang, T. L. Li, P. B. Sun*, 2016, “Peptides from hydrolysate of lantern fish (Benthosema pterotum) proved neuroprotective in vitro and in vivo”, JOURNAL OF FUNCTIONAL FOODS, 24, 438-449. (SCIE) (IF: 3.701; SCIE ranking: 22.3%,32.6%)

Liang, Chi-Ming

  • Ming-Yi Ho, Chi-Ming Liang*, Shu-Mei Liang*, 2016, “PATZ1 induces PP4R2 to form a negative feedback loop on IKK/NF-kB signaling in lung cancer”, Oncotarget, 7(32), 52255-52269.

Ma, Che Alex

  • Lee CP, Chiang SL, Ko AM, Liu YF, Ma C, Lu CY, Huang CM, Chang JG, Kuo TM, Chen CL, Tsai EM, Ko YC, 2016, “ALPK1 phosphorylates myosin IIA modulating TNF-alpha trafficking in gout flares.”, Scientific reports, 6, 25740. (SCIE) (IF: 3.998; SCIE ranking: 23.9%)
  • Chen CP, Lin MH, Chan YT, Chen LC, Ma C*, Fischer WB*, 2016, “Membrane protein assembly: two cytoplasmic phosphorylated serine sites of Vpu from HIV-1 affect oligomerization.”, Scientific reports, 6, 28866. (SCIE) (IF: 3.998; SCIE ranking: 23.9%)

Wong, Chi-Huey

  • S. Y. Tseng, W.-H. Cho, J. Su, S.-H. Chang, D. Chiang, C.-Y. Wu, C.-N. Hsiao, C.-H. Wong, 2016, “Preparation of Aluminum Oxide-Coated Glass Slides for Glycan Microarrays”, ACS Omega, 1(5), 773–783. (SCIE) (IF: 2.87; SCIE ranking: 45.8%)
  • D. Sok, M. Pauthner, B. Briney, J.-H. Lee, K. L.Saye-Francisco, J. Hsueh, A. Ramos, K.-M. Le, M. Jones, J. G. Jardine, R. Bastidas, A. Sarkar, C.-H. Liang, S. S. Shivatare, C.-Y. Wu, W. R. Schief, C.-H. Wong, I. A. Wilson, A. B. Ward, J. Zhu, P. Poignard, D. R. Burton, 2016, “A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans.”, Immunity, 45(1), 31-45. (SCIE) (IF: 22.553; SCIE ranking: 1.3%)
  • Y.-L. Lo, G.-G. Liou, C.-H. Lu, M. Hsiao, T.-L. Hsu, C.-H. Wong, 2016, “Dengue Virus Infection Is through a Cooperative Interaction between a Mannose Receptor and CLEC5A on Macrophage as a Multivalent Hetero-Complex.”, PloS one, 11(11), e0166474. (SCIE) (IF: 2.74; SCIE ranking: 38%)
  • D. T. MacLeod, N. M. Choi, B. Briney, F. Garces, L. S. Ver, E. Landais, B. Murrell, T. Wrin, W. Kilembe, C.-H. Liang, A. Ramos, C.-B. Bian, L. Wickramasinghe, L. Kong, K. Eren, C.-Y. Wu, C.-H. Wong, S. L. Kosakovsky Pond, I. A. Wilson, D. R. Burton, P. Poignard,, 2016, “Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch.”, Immunity, 44(5), 1215-1226. (SCIE) (IF: 22.553; SCIE ranking: 1.3%)
  • L. Krasnova and C.-H. Wong, 2016, “Exploring human glycosylation for better therapies.”, MOLECULAR ASPECTS OF MEDICINE, S0098-2997. (SCIE) (IF: 9.577; SCIE ranking: 5%,8.4%)
  • S.-C. Yeh, P.-Y. Wang, Y.-W. Lou, K.-H. Khoo, M. Hsiao, T.-L. Hsu, C.-H. Wong, 2016, “Glycolipid GD3 and GD3 synthase are key drivers for glioblastoma stem cells and tumorigenicity.”, Proceedings of the National Academy of Sciences of the United States of America, 113(20), 5592-5597. (SCIE) (IF: 9.412; SCIE ranking: 11.3%)
  • Y. Kizuka, S. Funayama, H. Shogomori, M. Nakano, K. Nakajima, R. Oka, S. Kitazume, Y. Yamaguchi, M. Sano, H. Korekane, T.-L. Hsu, H.-Y. Lee, C.-H. Wong and N. Taniguchi, 2016, “High-Sensitivity and Low-Toxicity Fucose Probe for Glycan Imaging and Biomarker Discovery.”, Cell Chemical Biology, 23(7), 782-792. (SCIE) (IF: 7.739; SCIE ranking: 10.1%)
  • S. S. Shivatare, S.-H. Chang, T.-I. Tsai, S. Y. Tseng, Y.-S. Lin, Y.-Y. Cheng, C.-T. Ren, S. Pawar, C.-S. Tsai, H.-W. Shi, Y.-F. Zeng, C.-H. Liang, P. D. Kwong, D. R. Burton, C.-Y. Wu and C.-H. Wong, 2016, “Modular synthesis of N-glycans and arrays for the hetero-ligand binding analysis of HIV antibodies”, Nature Chemistry, 8(4), 338-346. (SCIE) (IF: 21.687; SCIE ranking: 3.4%)
  • P.-C. Wang, J.-M. Fang, K.-C. Tsai, S.-Y. Wang, W.-I. Huang, Y.-S. Cheng, R. C., C.-H. Wong, 2016, “Peramivir Phosphonate Derivatives as Influenza Neuraminidase Inhibitors.”, Journal of medicinal chemistry, 59(11), 5297-5310. (SCIE) (IF: 6.205; SCIE ranking: 4.9%)
  • T.-N. Wu, K.-H. Lin, Y.-T. Wu, J.-R. Huang, J.-T. Hung, J.-C. Wu, C.-Y. Chen, K.-C. Chu, N.-H. Lin, A. L.Yu, C.-H. Wong, 2016, “Phenyl Glycolipids with Different Glycosyl Groups Exhibit Marked Differences in Murine and Human iNKT Cell Activation.”, ACS chemical biology, 11(12), 3431-3441. (SCIE) (IF: 4.434; SCIE ranking: 26.6%)
  • T.-C. Kuo, L.-W. Li, S.-H. Pan, J.-M. Fang, J.-H. Liu, T.-R. Cheng, C.-J. Wang, P.-F. Hung, H.-Y. Chen, T.-M. Hong, Y.-L .Hsu, C.-H. Wong, P.-C. Yan, 2016, “Purine-Type Compounds Induce Microtubule Fragmentation and Lung Cancer Cell Death through Interaction with Katanin.”, JOURNAL OF MEDICINAL CHEMISTRY, 59(18), 8521-8534. (SCIE) (IF: 6.205; SCIE ranking: 4.9%)
  • S. K. C. Cheung, P.-K. Chuang, H.-W. Huang, W. W. Hwang-Verslues, C. H.-H. Cho, W.-B. Yang, C.-N. Shen, M. Hsiao, T.-L. Hsu, C.-F. Chang, C.-H. Wong, 2016, “Stage-specific embryonic antigen-3 (SSEA-3) and β3GalT5 are cancer specific and significant markers for breast cancer stem cells.”, Proceedings of the National Academy of Sciences of the United States of America, 113(4), 960-965. (SCIE) (IF: 9.412; SCIE ranking: 11.3%)
  • C.-H. Hsu, S. Park, D. E. Mortenson, B. L. Foley, X. Wang, R. J. Woods, D. A. Case, E. T. Powers, C.-H. Wong, H. J. Dyson, J. W. Kelly, 2016, “The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.”, Journal of the American Chemical Society, 138(24), 7636-7648. (SCIE) (IF: 14.612; SCIE ranking: 7.3%)
  • G. B. E. Stewart-Jones, C. Soto, T. Lemmin, G.-Y. Chuang, A. Druz, R. Kong, P. V. Thomas, K. Wagh, T. Zhou, A.-J. Behrens, T. Bylund, C. W. Choi, J. R. Davison, I. S. Georgiev, M. G. Joyce, Y. D. Kwon, M. Pancera, J. Taft, Y. Yang, B. Zhang, S. S. Shivatare, V. S. Shivatare, C.-C. D. Lee, C.-Y. Wu, C. A. Bewley, D. R. Burton, W. C. Koff, M. Connors, M. Crispin, B. T. Korber, C.-H. Wong, J. R. Mascola and P. D. Kwong, 2016, “Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G.”, Cell, 165(4), 813-826. (SCIE) (IF: 38.637; SCIE ranking: 1%,0.3%)
  • L. Krasnova and C.-H. Wong, 2016, “Understanding the Chemistry and Biology of Glycosylation with Glycan Synthesis”, Annual Review of Biochemistry, 85, 599-630. (SCIE) (IF: 25.787; SCIE ranking: 1%)

Wu, Chung-Yi

  • Susan Yu Tseng, Wen-Hao Cho, James Su, Shih-Huang Chang, Donyau Chiang, Chung-Yi Wu, Chien-Nan Hsiao, Chi-Huey Wong*, 2016, “Preparation of Aluminum Oxide-Coated Glass Slides for Glycan Microarrays.”, ACS Omega, 1, 773-783. (SCIE) (IF: 2.87; SCIE ranking: 45.8%)
  • Devin Sok, Mattias Pauthner, Bryan Briney, jeong Hyun Lee, Karen J Save-Francisco, Jessica Hsueh, Alejandra Ramos, Khoa M Le, Meaghan Jones, Joseph G Jardine, Raiza Bastidas, Anita Sarkar, Chi-Hui Liang, Sachin S Shivatare, Chung-Yi Wu, William R Schief, Chi-Huey Wong, Ian A Wilson, Andrew B Ward, Jiang Zhu, Pascal Poignard, Dennis R Burton*, 2016, “A prominent site of antibody vulnerability on HIV envelope incorporates a motif associated with CCR5 binding and its camouflaging glycans.”, IMMUNITY, 45, 31-45. (SCIE) (IF: 22.553; SCIE ranking: 1.3%)
  • Daniel T Macleod, Nancy M Choi, Bryan Briney, Fernando Garces, Lorena S, Ver, Elise Landais, Ben Murrell, Terri Wrin, William Kilembe, Chi-Hui Liang Alejandra Ramos, Chaoran B Bian, Lalinda Wickramasinghe, Leopold Kong, Kemal Eren, Chung-Yi Wu, Chi-Huey Wong, Sergei L Kosakovsky Pond, Ian A Wilson, Bennis R Burton, Pascal Poignard*., 2016, “Early antibody lineage diversification and independent limb maturation lead to broad HIV-1 neutralization targeting the Env high-mannose patch.”, IMMUNITY, 44, 1215-1226. (SCIE) (IF: 22.553; SCIE ranking: 1.3%)
  • Jiahn-Haur Liao, Chih-Ta Henry Chien, Han-Ying Wu, Kai-Fa Huang, Iren Wang, Meng-Ru Ho, I-Fan Tu, I-Ming Lee, Wei Li, Yu-Ling Shih, Chung-Yi Wu, Pavel A. Lukyanov, Shang-TeDanny Hsu, Shih-Hsiung Wu , 2016, “A multivalent marine lectin from Crenomytilus grayanus possesses anti-cancer activity through recognizing globotriose Gb3.”, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 138(14), 4787-4795. (SCIE) (IF: 14.612; SCIE ranking: 7.3%)
  • Sachin S Shivatare, Shih-Huang Chang, Tsung-I Tsai, Susan Yu Tseng, Yih-Shyan Lin,Yang-Yu Cheng, Chien-Tai Ren, Chang-Chun David Lee, Sujeet Pawar, Charng-Sheng Tsai,Hao-Wei Shih, Yi-Fang Zeng, Chi-Hui Liang Peter D. Kwong, Dennis R. Burton, Chung-Yi Wu,* Chi-Huey Wong*, 2016, “Modular synthesis of N-glycans and arrays for the hetero-ligand binding analysis of HIV antibodies”, Nature Chemistry, 8(4), 338-346. (SCIE) (IF: 21.687; SCIE ranking: 3.4%)
  • Guillaume B. E. Stewart-Jones, Cinque Soto, Thomas Lemmin, Gwo-Yu Chuang, Aliaksandr Druz, Rui Kong, Paul V. Thomas, Kshitij Wagh, Tongqing Zhou, Anna-Janina Behrens, Tatsiana Bylund, Chang W. Choi, Jack R. Davison, Ivelin S. Georgiev, M. Gordon Joyce, Young Do Kwon, Marie Pancera, Justin Taft, Yongping Yang, Baoshan Zhang, Sachin S. Shivatare, Vidya S. Shivatare, Chang-Chun D. Lee, Chung-Yi Wu, Carole A. Bewley, Dennis R. Burton,, Wayne C. Koff, Mark Connors, Max Crispin, Ulrich Baxa, Bette T. Korber, Chi-Huey Wong, John R. Mascola and Peter D. Kwong*, 2016, “Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G.”, CELL, 165(4), 813-826. (SCIE) (IF: 38.637; SCIE ranking: 1%,0.3%)
  • Primadona Indah, Lai Yin-Hung, Capangpangan Rey Y., Obena Rofeamor P., Tseng Mei-Chun, Huang Ming-Feng, Chang Huan-Tsung, Li Shiou-Ting, Wu Chung-Yi, Chien Wei-Ting, Lin Chun-Cheng, Wang Yi-Sheng, Chen Yu-Ju, 2016, “Functionalized HgTe nanoparticles promote laser-induced solid phase ionization/dissociation for comprehensive glycan sequencing”, The Analyst, 141(21), 6093-6103. (SCIE) (IF: 3.978; SCIE ranking: 17.4%)

Yang, An-Suei

  • Hou SC, Chen HS, Lin HW, Chao WT, Chen YS, Fu CY, Yu CM, Huang KF, Wang AH, Yang AS*, 2016, “High throughput cytotoxicity screening of anti-HER2 immunotoxins conjugated with antibody fragments from phage-displayed synthetic antibody libraries.”, Scientific reports, 6, 31878. (SCIE) (IF: 3.998; SCIE ranking: 23.9%)
  • Jian JW, Elumalai P, Pitti T, Wu CY, Tsai KC, Chang JY, Peng HP, Yang AS*, 2016, “Predicting Ligand Binding Sites on Protein Surfaces by 3-Dimensional Probability Density Distributions of Interacting Atoms.”, PloS one, 11(8), e0160315. (SCIE) (IF: 2.74; SCIE ranking: 38%)