語言

Yang, Wen-Bin

YangWB_6x7Senior Research Specialist

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EDUCATION AND POSITIONS HELD:

  • B. S., in Chemistry, ChungYuanChristianUniversity, Taiwan R.O.C., 1989–1992
  • M. S., Department of Chemistry, National Chung Hsing University, 1992–1994
  • Ph.D., Department of Chemistry, National Taiwan University, 1994–1998
  • Postdoctoral Research Fellow, Institute of Biological Chemistry, Academia Sinica, 1998–2002
  • Assistant Professor, Graduate Institute of Pharmacognosy Science, Taipei Medical University, 2002–2003
  • Assistant Research Fellow, GenomicsResearchCenter, Academia Sinica, 2003–2013
  • Associate Research Specialist, Genomics Research Center, Academia Sinica, Taiwan, 2013-2018
  • Senior Research Specialist, Genomics Research Center, Academia Sinica, 2018-present

HONORS:

  • Fellowship of Ministry of Education and NSC, 1992–1994
  • Graduate Fellowship of National Science Council (NSC), 1994–1998
  • The best research paper in Journal of the Chinese Chemical Society, 2000
  • Postdoctoral fellowship in Academia Sinica, 1998–2002

RESEARCH INTERESTS:

The main interest of our group is the structural determination of polysaccharides in medicinal herbs. Polysaccharides such as Ganoderma lucidum (靈芝), Dendrobium houshanens (霍山石斛) and Cordyceps sinensis (冬蟲夏草) were isolated to study their biological activities and structural SAR. For characterization of polysaccharides we used HPAEC, GC-MS, CE, NMR, glycanase and MALDI-MS spectrum to investigate structures of oligosaccharides and polysaccharides. We also developed some convenient and efficient methods to label poly-, oligosaccharides which can be useful on purification and detection. A series of aldose-imidazole and aldose-bis-indole derivatives with fluorescence active was synthesized for composition analysis and chiral resoluation of monosaccharides from medicinal herbs. Research work in Yang laboratory covers several areas:

  • Organic chemistry
  • Carbohydrates chemistry
  • Natural product chemistry
  • Saccharides analytic chemistry
  • Asymmetric catalytic reaction

SELECTED PUBLICATIONS: