Senior research scientist

tingjenc
+886-2-27871267

EDUCATION AND POSITIONS HELD:

• B.Eng, Chemical Engineering, National Tsing Hua University, Taiwan, 1993
• Ph.D., Life Sciences, National Tsing Hua University, Taiwan, 1999
• Post-doctoral Research Associate, Keck Graduate Institute of Applied Life Science, USA, 2000-2004
• Assistant Research scientist, Genomics Research Center, Academia Sinica, 2005-2008
• Associate Research scientist, Genomics Research Center, Academia Sinica, 2008-2012
• Senior research scientist, Genomics Research Center, Academia Sinica, 2012-present

EXPERTISE:

Development of biological assays for functional evaluation of therapeutically significant targets or molecules.

RESPONSIBILITY:

My main responsibilities towards GRC mission is to develop bioassay platforms for high-throughput screening, to conduct activity evaluations for lead identification/optimization, and to support the needs in assay development for researchers with main focuses on:

I. High-Throughput Screening

• Design and develop high-throughput compatible target- and cell-based assays
• Conduct high-throughput screening and hit confirmation
• Support further studies for lead identification/optimization

II. Assay Development

• Develop assays and evaluate inhibitor potencies for cell-wall synthesis enzymes to support efforts in discovery of small molecules against methicillin-resistant Staphylococcus aureus, Mycobacterium tuberculosis, and Gram-negative bacteria
• Support the needs for reagent preparation and for animal studies in vaccine as well as therapeutics evaluation for infectious diseases and cancer
• Evaluate the biological activities of fractions and small molecules derived from Chinese medicinal herbs to support the identification of active molecules for drug discovery

SELECTED PUBLICATIONS: