EDUCATION AND POSITIONS HELD:

• B.S., California Institute of Technology, 1971-1974
• M.D., Harvard Medical School, 1974-1978
• Physician and Research Scientist, Cedars-Sinai Medical Center, 1986-1990
• Assistant Professor through Associate Professor of Medicine in Residence, UCLA School of Medicine, 1989-1990
• Professor of Medicine and Microbiology, NYU School of Medicine, 1990-1996
• Scientific Director and Chief Executive Officer, Aaron
• Diamond AIDS Research Center, 1990-present
• Professor and Physician, The Rockefeller University, 1996-present

HONORS:

• Man of the Year, Time Magazine, 1996
• Member, Institute of Medicine, National Academy of Sciences, 1997
• Scientific Honoree, New York Academy of Medicine, 1998
• Member, Academia Sinica, Republic of China, 1998
• Presidential Citizens Medal, 2001
• Friendship Award, State Council of the People's Republic of China, 2003
• Sydney Rubbo Award, Australia Society of Microbiology, 2003
• Edward Ahrens Award in Clinical Investigation, 2003
• Lewis and Jack Rudin New York Prize for Medical Research, 2003
• Foreign Member, Chinese Academy of Engineering, 2003
• Board of Overseers, Harvard University, 1998-2004
• Board member, the MIT Corporation, 2003-present

RESEARCH INTERESTS:

Therapeutic studies on AIDS and other virus-mediated diseases

Dr. Ho's research interest is to elucidate the dynamic nature of HIV replication in AIDS patients and to halt the spread of the AIDS epidemic. This basic understanding led Dr. Ho and his coworkers to champion combination antiretroviral therapy, including the use of protease inhibitors, that has resulted in dramatic reductions in AIDS-associated mortality in developed countries since 1996. Dr. Ho continues to pursue therapeutic studies that attempt to eradicate HIV. In addition, his research team is now devoting considerable efforts to develop a vaccine to halt the spread of the AIDS epidemic. Furthermore, he will apply the knowledge and methodology to development vaccines against influenza/avian influenza in the near future.

何大一院士的研究工作主要致力於研究人類免疫缺乏病毒的特性，以便遏止愛滋病的蔓延。藉由對人類免疫缺乏病毒的了解，何院士發明對抗愛滋病的雞尾酒療法， 其中包含蛋白水解酶抑制劑的使用。自從1996年起已有效降低已開發國家愛滋病患者的死亡率，並試圖全面撲滅愛滋病。其研究團隊正積極研發抗體以阻止愛滋病的散佈。此外，何院士也計畫運用類似的概念與技術，研發對抗流行性感冒/禽流感的抗體。