Distinguished Research Fellow
Proteomics and Structural Biology Program Director

EDUCATION AND POSITIONS HELD:

• B.S., M.S., Chemistry, National Taiwan University, 1967, 1970
• Ph.D., Chemistry, University of Illinois-Urbana, 1974
• Postdoctoral Research Associate through Senior Research Scientist, Biology, MIT, 1974–1988
• Professor of Biophysics, Biochemistry and Chemistry, University of Illinois-Urbana, 1988–2000
• Distinguished Research Fellow and Director, Institute of Biological Chemistry, Academia Sinica, 2000–present
• Editor, European Journal of Biochemistry, 1995–2002
• Editorial Board, Nucleic Acids Research, 1998–2002
• President, Taiwan Society of Biochemistry and Molecular Biology, 2001–2004
• President, Taiwan Biophysical Society, 2001–present
• President, Taiwan Proteomics Society, 2003–present
• Council Member, HUPO and AOHUPO, 2003–present

HONORS:

• Elected member, American Society for Biochemistry & Molecular Biology, 1987
• Fellow, American Association for the Advancement of Science, 1998
• Academician, Academia Sinica, 2000

RESEARCH INTERESTS:

Dr. Wang’s research interest is to apply structural proteomics in understanding the functions of important biological systems. Our primary technology platforms are high-throughput protein synchrotron crystallography and proteomics. Other advanced technologies will be employed if necessary. At present, we are working in several areas including (1) Structural enzymology: Several enzyme families as potential targets for drug discovery, including prenyltransferases, glyco-related enzymes, proteases and phosphatases, are under investigation. (2) Protein–DNA and anticancer drug–DNA interactions, (3) Search for disease markers using proteomic analysis: We use advanced proteomic approaches to analyze cells and tissues that are associated with certain diseases to identify potential marker proteins, particularly using body fluid samples, including blood, (4) Proteins from extreme environments.