Research Fellow

EDUCATION AND POSITIONS HELD:

• Ph. D., Biochemistry, University of Maryland at College Park (1994)
• Postdoctoral Fellow, Yale University (1994-1996)
• Investigator, SmithKline Beecham Pharmaceuticals (1996-1999)
• Assistant Research Fellow (1999-2002) and Associate Research fellow (2002-present), Institute of Biological Chemistry, Academia Sinica

HONORS:

• 中研院年輕學者研究著作獎

RESEARCH INTERESTS:

Structure and function of prenyltransferases, proteases and phosphatases; Enzyme reaction mechanism and fast kinetics; Inhibitor design and drug discovery; Protein engineering for new activity; Kinetics and thermodynamics of protein-protein interaction; antibiotics and resistance; innate immunity

Structure	Kinetics	Mechanism