化學生物學研究領域 2018

Chen, Yun-Ru Ruby

  • Ming-Che Lee, Wan-Cheng Yu, Yao-Hsiang Shih, Chun-Yu Chen, Zhong-Hong Guo, Shing-Jong Huang, Jerry C. C. Chan, and Yun-Ru Chen*, 2018, “Zinc ion rapidly induces toxic, off-pathway amyloid-β oligomers distinct from amyloid-β derived diffusible ligands in Alzheimer’s disease”, Scientific Reports, 8, 4772. (SCI)

Cheng, Wei-Chieh

  • Cheng WC, Lin CK, Li HY, Chang YC, Lu SJ, Chen YS, Chang SY, 2018, “A combinatorial approach towards the synthesis of non-hydrolysable triazole-iduronic acid hybrid inhibitors of human alpha-l-iduronidase: discovery of enzyme stabilizers for the potential treatment of MPSI.”, CHEMICAL COMMUNICATIONS, 54(21), 2647-2650. (SCI)
  • Li HY, Lee JD, Chen CW, Sun YC, Cheng WC, 2018, “Synthesis of (3S,4S,5S)-trihydroxylpiperidine derivatives as enzyme stabilizers to improve therapeutic enzyme activity in Fabry patient cell lines.”, European journal of medicinal chemistry, 144, 626-634. (SCI)

Li, Tsung-Lin

  • N. S. Hsu, Y. L. Wang, K. H. Lin, C. F. Chang, S. Y. Lyu, L. J. Hsu, Y. C. Liu, C. Y. Chang, C. J. Wu, T. L. Li*, 2018, “The Mesomeric Effect of Thiazolium on non-Kekule Diradicals in Pichia stipitis Transketolase”, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 57(7), 1802-1807. (SCI)

Wong, Chi-Huey

  • H.-W. Cheng, R.-J. Chein, T.-J. Cheng, P.-S. Wu, H.-Y. Wu, P.-F. Hung, C.-J. Wang, Y.-L. Hsu, J.-M. Wong, A. Yuan, C.-H. Wong, P.-C. Yang, S.-H. Pan, 2018, “2-anilino-4-amino-5-aroylthiazole-type compound AS7128 inhibits lung cancer growth through decreased iASPP and p53 interaction.”, Cancer science, 109(3), 832-842. (SCI)
  • T. Zhou, A. Zheng, U. Baxa, G.-Y. Chuang, I. S. Georgiev, R. Kong, S. O’Dell, S. Shahzad-ul-Hussan, C.-H. Shen, Y. Tsybovsky, R. T. Bailer, S. K. Gift, M. K. Louder, K. McKee, R. Rawi, C. H. Stevenson, G. B. E. Stewart-Jones, J. D. Taft, E. Waltari, Y. Yang, B. Zhang, S. S. Shivatare, V. S. Shivatare, C.-C. D. Lee, C.-Y. Wu, NISC Comparative Sequencing Program, J. C. Mullikin, C. A. Bewley, D. R. Burton, V. R. Polonis, L. Shapiro, C.-H. Wong, J. R. Mascola, P. D. Kwong, and X. Wu, 2018, “A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope.”, Immunity, 48(3), 500-513.e6. (SCI)
  • W.-S. Wu, W.-C. Cheng, T.-R. Cheng, C.-H. Wong, 2018, “Affinity-Based Screen for Inhibitors of Bacterial Transglycosylase.”, Journal of the American Chemical Society, 140(8), 2752-2755. (SCI)
  • S. S. Shivatare, V. S. Shivatare, C.-Y. Wu, C.-H. Wong, 2018, “Chemo-Enzymatic Synthesis of N-Glycans for Array Development and HIV Antibodies Profiling”, Jove-Journal of Visualized Experiments, 132. (SCI)
  • S. S. Shivatare, L.-Y. Huang, Y.-F. Zeng, J.-Y. Liao, T.-H. You, S.-Y. Wang, T. Cheng, C.-W. Chiu, P. Chao, L.-T. Chen, T.-I. Tsai, C.-C. Huang, C.-Y. Wu, N.-H. Lin, and C.-H. Wong, 2018, “Development of glycosynthases with broad glycan specificity for the efficient glyco-remodeling of antibodies”, CHEMICAL COMMUNICATIONS, 54(48), 6161-6164. (SCI)
  • C.-F. Huang, K. S. Liang, T.-L. Hsu, T.-T. Lee, Y.-Y. Chen, S.-M. Yang, H.-H. Chen, S.-H. Huang, W.-H. Chang, T.-K. Lee, P. Chen, K.-E. Peng, C.-C. Chen, C.-Z. Shi, Y.-F. Hu, G. Margaritondo, T. Ishikawa, C.-H. Wong and Y. Hwu, 2018, “Free-electron-laser coherent diffraction images of individual drug-carrying liposome particles in solution.”, Nanoscale, 10(6), 2820-2824. (SCI)
  • C.-P. Liu, T.-I Tsai, T. Cheng, V. S. Shivatare, C.-Y. Wu, C.-Y. Wu, C.-H. Wong, 2018, “Glycoengineering of antibody (Herceptin) through yeast expression and in vitro enzymatic glycosylation.”, Proceedings of the National Academy of Sciences of the United States of America, 115(4), 720-725. (SCI)
  • P.-W. Lo, J.-J. Shie, C.-H. Chen, C.-Y. Wu, T.-L. Hsu, C.-H. Wong, 2018, “O-GlcNAcylation regulates the stability and enzymatic activity of the histone methyltransferase EZH2”, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, doi: 10.1073. (SCI)
  • S. Dey and C.-H. Wong, 2018, “Programmable one-pot synthesis of heparin pentasaccharides enabling access to regiodefined sulfate derivatives”, Chemical Science, DOI: 10.1039/C8SC01743C. (SCI)
  • X. Wang, L. Krasnova, K. B. Wu, W.-S. Wu, T.-J. Cheng, C.-H. Wong, 2018, “Towards new antibiotics targeting bacterial transglycosylase: Synthesis of a Lipid II analog as stable transition-state mimic inhibitor.”, Bioorganic & medicinal chemistry letters, pii: S0960-894X(18)30228-2. (SCI)
  • V. S. Shivatare, S. S. Shivatare, C.-C. Lee, C.-H. Liang, K.-S. Liao, Y.-Y. Cheng, G. Saidachary, C.-Y. Wu, N.-H. Lin, P. D. Kwong, D. Burton, C.-Y. Wu, C.-H. Wong, 2018, “Unprecedented Role of Hybrid N-Glycans as Ligands for HIV-1 Broadly Neutralizing Antibodies.”, Journal of the American Chemical Society, 140(15), 5202-5210. (SCI)

Wu, Chung-Yi

  • Lee I-Ming, Yang Feng-Ling, Chen Te-Li, Liao Kuo-Shiang, Ren Chien-Tai, Lin Nien-Tsung, Chang Yu-Pei, Wu Chung-Yi*, Wu Shih-Hsiung*, 2018, “Pseudaminic acid on exopolysaccharide of Acinetobacter baumannii plays a critical role in phage-assisted preparation of glycoconjugate vaccine with high antigenicity.”, Journal of the American Chemical Society, 140, online. (SCI)
  • Shivatare Sachin S., Huang Lin-Ya, Zeng Yi-Fang, Liao Jung-Yu, You Tsai-Hong, Wang Shi-Yun, Cheng Ting, Chiu Chih-Wei, Chao Ping, Chen Li-Tzu, Tsai Tsung-I, Huang Chiu-Chen, Wu Chung-Yi*, Lin Nan-Horng*, Wong Chi-Huey*, 2018, “Development of glycosynthases with broad glycan specificity for the efficient glyco-remodeling of antibodies”, Chemical Communications, 54(48), 6161-6164. (SCI)
  • Shivatare Vidya S., Shivatare Sachin S., Lee Chang-Chun David, Liang Chi-Hui, Liao Kuo-Shiang, Cheng Yang-Yu, Saidachary Gannerla, Wu Chung-Yi, Lin Nan-Horng, Kwong Peter D., Burton Dennis R., Wu Chung-Yi*, Wong Chi-Huey*, 2018, “Unprecedented Role of Hybrid N-Glycans as Ligands for HIV-1 Broadly Neutralizing Antibodies”, Journal of the American Chemical Society, 140(15), 5202-5210. (SCI)
  • Zhou Jie, Wei Jianjian, Choy Ka-Tim, Sia Sin Fun, Rowlands Dewi K., Yu Dan, Wu Chung-Yi, Lindsley William G., Cowling Benjamin J., McDevitt James, Peiris Malik, Li Yuguo, Yen Hui-Ling, 2018, “Defining the sizes of airborne particles that mediate influenza transmission in ferrets”, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115(10), E2386-E2392. (SCI)
  • Tongqing Zhou, Anqi Zheng, Ulrich Baxa, Gwo-Yu Chuang, Ivelin S. Georgiev, Rui Kong, Sijy O'Dell, Syed Shahzad-ul-Hussan, Chen-Hsiang Shen, Yaroslav Tsybovsky, Robert T. Bailer, Syna K. Gift, Mark K. Louder, Krisha McKee, Reda Rawi, Catherine H. Stevenson, Guillaume B. E. Stewart-Jones, Justin D. Taft, Eric Waltari, Yongping Yang, Baoshan Zhang, Sachin S. Shivatare, Vidya S. Shivatare, Chang-Chun D. Lee, Chung-Yi Wu, NISC Comparative Sequencing Program, James C. Mullikin, Carole A. Bewley, Dennis R. Burton, Victoria R. Polonis, Lawrence Shapiro, Chi-Huey Wong, John R. Mascola,* Peter D. Kwong* and Xueling Wu*, 2018, “Structural Basis of Recognition by an Antibody Targeting the Silent Face of HIV Envelope”, IMMUNITY, 48(3), 500-513. (SCI)
  • Shivatare Sachin S., Shivatare Vidya S., Wu Chung-Yi, Wong Chi-Huey*, 2018, “Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling”, Jove-Journal of Visualized Experiments, 132, e55855. (SCI)
  • Chiu-Ping Liu, Tsung-I Tsai, Ting Cheng, Vidya S. Shivatare, Chung-Yi Wu, Chung-Yi Wu, and Chi-Huey Wong*, 2018, “Glycoengineering of antibody (Herceptin) through yeast expression and in vitro enzymatic glycosylation”, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115(4), 720-725. (SCI)
  • Lo Pei-Wen, Shie Jiun-Jie, Chen Chein-Hung, Wu Chung-Yi, Hsu Tsui-Ling, Wong Chi-Huey, 2018, “O-GlcNAcylation regulates the stability and enzymatic activity of the histone methyltransferase EZH2”, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115, in press.

Language

論文集