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Novel mechanism for DNA damage signal transduction
Imbalance of tumor suppressor genes and oncogenes caused by gene mutations has been proven to directly contribute to tumorigenesis. The gene mutations occur due to fact that the DNA repair could not be fully completed during the cell cycle. Both DNA replication without proofreading and exogenous genomic insults such as UV light, irradiation, toxin, or carcinogen lead to gene mutations. In order to tolerate the exogenous genomic insults and ensure the fidelity of DNA replication, the cell cycle checkpoints have been evolved as mechanisms to stabilize the genomic integrity in all eukaryotic cells. Therefore, to understand how the cell cycle checkpoints are regulated is consequential to uncovering the mechanism of tumorigenesis.
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ˇ§2008 Summer Special Feature -the world of the budding yeastˇ¨ start enrolling!
Time: Mon/Wed; 9 - 10:30 AM Begin on July 16th for a total of 12 lectures
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Collaborated Research Shed Lights on Potential Therapeutics for Dengue Fever
On May 21th (US.PDT), the Nature Advance Online ...
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GRC Lecture Notices
Check out recent lectures in the Events section...
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New Research Faculty Positions Available at GRC
Research Faculty Positions Available in Chemical Biology, Key Technology Development...areas
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